Question

Create a mechanism for the following reagents: 1,2,3,4,5,6,7,8-octahydro-napthalene, osmium tetraoxide, and water in order to create...

Create a mechanism for the following reagents: 1,2,3,4,5,6,7,8-octahydro-napthalene, osmium tetraoxide, and water

in order to create cis-octahydro-naphthalene-4a,8a-diol

Homework Answers

Answer #1

Alkenes add to OsO4 to give diolate species that hydrolyze to cis-diols. The net process is called dihydroxylation. This proceeds via a [3 + 2] cycloaddition reaction between the OsO4 and alkene to form an intermediate osmate ester which rapidly hydrolyses to yield the vicinal diol. As the oxygen atoms are added in a concerted step, the resulting stereochemistry is cis. The general mechanism of alkene with OsO4 is described as follow

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
What is the mechanism for Alkene Dihydroxylation reaction of cis-octahydro-naphthalene-4a,8a-diol, the starting materials are 1,2,3,4,5,6,7,8-Octahydro-naphthalene and...
What is the mechanism for Alkene Dihydroxylation reaction of cis-octahydro-naphthalene-4a,8a-diol, the starting materials are 1,2,3,4,5,6,7,8-Octahydro-naphthalene and OsO4?
please create a bode plot for the following tf in matlab 1/(Ts+1), first order equation
please create a bode plot for the following tf in matlab 1/(Ts+1), first order equation
rank the following compounds in order of increasing solubility in water. propanol, ethanol and hexanol
rank the following compounds in order of increasing solubility in water. propanol, ethanol and hexanol
Rank the following molecules in decreasing order of their solubility in water (start with the most...
Rank the following molecules in decreasing order of their solubility in water (start with the most soluble). Hexane Pentanol Ethanoic Acid Cyclooctanol
Canada's Water Policy: Explain would the following policy reforms listed below, create a more efficient and...
Canada's Water Policy: Explain would the following policy reforms listed below, create a more efficient and sustainable water industry for Canada: - implement universal residential water metering - move to full cost accounting - institute seasonal surcharges to better reflect the marginal costs of water use during peak summer months; and - amalgamate smaller, high-cost water agencies to exploit scale economies and promote innovation.
Canada's Water Policy: Explain would the following policy reforms listed below, create a more efficient and...
Canada's Water Policy: Explain would the following policy reforms listed below, create a more efficient and sustainable water industry for Canada: - implement universal residential water metering - move to full cost accounting - institute seasonal surcharges to better reflect the marginal costs of water use during peak summer months; and - amalgamate smaller, high-cost water agencies to exploit scale economies and promote innovation.
Propose a reaction mechanism for the following: Mg(s)+2HCl(aq)---->H2(aq)+MgCl2(aq) The reaction order is 4; Rate=k〖[HCl]〗^2 〖[Mg]〗^2 I...
Propose a reaction mechanism for the following: Mg(s)+2HCl(aq)---->H2(aq)+MgCl2(aq) The reaction order is 4; Rate=k〖[HCl]〗^2 〖[Mg]〗^2 I need help determining the elementary steps as chemical equations
Place the following in order of increasing entropy 1) a system of 1 mole water and...
Place the following in order of increasing entropy 1) a system of 1 mole water and 1 mole alcohol, separated, at 50 ° C 2) a system of 1 mole water mixed with 1 mole alcohol, at 50 ° C 3) 1 mole ice, at 0° C 4) 1mole water at 0° C
Part A Rank the following substances in order from most soluble in water to least soluble...
Part A Rank the following substances in order from most soluble in water to least soluble in water: methane, CH4; 2-pentanol, C5H11OH; lithium nitrate, LiNO3; and ethane, C2H6. Rank from most to least soluble in water. To rank items as equivalent, overlap them.
String array operations a. Create a string array called myInformationcontaining the following entries in order: Your...
String array operations a. Create a string array called myInformationcontaining the following entries in order: Your full name The name of the town or city where you were born Your major The name of this university with only the first letter of each word capitalized; don’t forget the “The”! b. Use the Matlab function strcmp to compare the name of the university as you defined it against the following two strings: i. “The Ohio State University” ii. “THE OHIO STATE...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT