Question

Why are the solutions filtered prior to injection onto the UPLC column?

Answer 1

*If not filtered it will block the column or chock column and injector port and may lead to damage of the costly column.

*and also By filtering , we can reduce debris capable of plugging the sinker and column frits, causing contamination, damaging pump valves, blocking capillaries, causing poor peak performance, and contributing extra peaks and excessive chromatographic noise.

*Filtering your sample prior to injection can prolong your injector and column life.