Question

Would you potentially enjoy drugs that enhance glutamate activity? GABA activity? What are some risks and...

Would you potentially enjoy drugs that enhance glutamate activity? GABA activity? What are some risks and benefits associated with each?

Why might drugs impacting glutamate NMDA activity be potential targets for improving learning and memory? Why might glutamate NMDA agonists be dangerous to brain health?

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Answer #1

Riluzole is the drug which enhances glutamate activity by increasing glutamate reuptake into glial cells or decreases glutamate release.

Tiagabine is the drug which enhances GABA activity.

DRUGS BENEFITS RISK
RILUZOLE used to treat nerve disease such as ALS(amylotrophic lateral sclerosis) it causes dizziness, diarrhea, loss of appetite, stomach pain.
TIAGABINE used to treat focal seizures. change in body balance,tiredness, sleepy.

The drugs impacting glutamate NMDA activity targets for improving learning and memory as the NMDA receptor channels plays imprtant role in synaptic plasticity and synapse formation underlying memory, learning and formation of neural network. and NMDA regulate physiologic substrate for memory function in brain.

Glutamate NMDA agonists be dangerous to brain health as glutamate induced neurotoxicity and recognize as dangerous signal in brain.

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