Question

Compare and contrast lipid soluble and amino acid derived hormones. What is an example of each of these types of hormones? How do lipid soluble and amino acid derived hormones cause a response in a cell? describe the steps of signal transduction for both lipid soluble and amino acid derived hormones. How are they the same, and how are they different?

Answer 1

lipid soluble or Steroid hormones exert their function much faster than peptide hormones. In general, the receptors for the lipid soluble hormones are located in the cytosol or in the nucleus. Since these steroid hormones are soluble in lipids, they can easily pass through cellular and nuclear membranes. Once inside the cell, the steroid hormone binds to a specific receptor in the cytosol. The lipid hormone-receptor complex translocates into the nucleus and binds to another specific receptor on the chromatin to alter gene expression.

Peptide hormones are hydrophilic, large polypeptides which bind to receptors on the cell membrane that generate second messengers which result in modification of enzyme activity.

lipid soluble hormones are much quicker in action than the peptide hormones.