Question

How the Bee's P450 activity works in detoxifying the body?

Answer 1

Cytochrome p450 has monooxygenase activity it detoxifies phytochemicals in honey any and pollen.neonicotinoids are present in insecticides which are the main reason of reduction in population of bees.enzymep450 has the capability of metabolize at least one of the neonicotinoids into a less toxic derivative.Neonicotinoids target acetylcholine receptors in insects central neevous system.honey bees produce flavonols which are mostly produced in pollen guring germination p450 helps to destroy harmful flavonols in honey bee it is mainly quercetin and kaemferol.out of quercitin is produced maximally as it is also produced with nectars it is the main flavonol which maintains fertility in honey . cytochromec p 450 metabolize this flavonol..cytochrome p 450 superfamily consists of variety of cytochrome oxygenase enzyme and they detoxify the body of bees.