Question

Thr-91 of Complex I is conserved through evolution. It is crucial for the functioning of Complex...

Thr-91 of Complex I is conserved through evolution. It is crucial for the functioning of Complex I in the ETC. I make two forms of mutant yeast: one in which Thr-91 is mutated to an alanine (Thr91Ala) and another in which Thr-91 is mutated to a tryptophan (Thr91Trp).

What is the different between the mutations and what other information can I derive from this?

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

The change of amino acid from therionine to alanine will result in change of polar amino acid to non polar which can alter the folding of protein and function also. The OH group of therionine may also be required for functioning of normal protein. The changes would affect more if both the mutations are occurring in active site of the protein. The change to tryptophan also result in same effects. The polar amino acid will change to other side chain containing amino acid.

The other information which can be derived from this is regarding codon changes and nucleotide changes in protein coding DNA sequence. Thus info can be deduced from different codons.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Hey i just read your comment and you just need to answer do you agree or...
Hey i just read your comment and you just need to answer do you agree or disagree with ir and explain My Teacher gave this answer and we need to response this answer You need to response this answer why you agree with it or why you disagree and explain You have Two Answer you need to response on your own word Reactions may include: feedback, agreements, disagreements, etc. with supporting facts, material, citations, etc. to support your reaction (or...
Review the discussions below and reply your thoughts on each discussion: Discussion 1 I believe there...
Review the discussions below and reply your thoughts on each discussion: Discussion 1 I believe there are many reasons why the knowledge-doing gap has become so common within organizations. For one, I feel that many are faced with obstacles that require some thinking outside the box. Sometimes, you may have to take some steps outside the normal regimen to figure new approaches to solving a problem, and some can be either uncomfortable with this approach or simply unaware of where...
Following is the whole proposal and for that I need a logical design (ERD), Q. Map...
Following is the whole proposal and for that I need a logical design (ERD), Q. Map all different types of entities and relationships, provide definitions of entities and relationships. Zameen.com is Pakistan's first and biggest property portal and is amongst the world's top five property portals. It was founded in 2006 and has since revolutionized Pakistan's real estate industry by linking online buyers and sellers in a very convenient way, making it a worldwide household name among Pakistanis. This is...
I completed everything except for the last part. I know my answers are right because i...
I completed everything except for the last part. I know my answers are right because i double checked but i just dont know how to answer the last section. Problem 3-1 Schedule C (LO 3.1) Scott Butterfield is self-employed as a CPA. He uses the cash method of accounting, and his Social Security number is 644-47-7833. His principal business code is 541211. Scott's CPA practice is located at 678 Third Street, Riverside, CA 92860. Scott’s income statement for the year...
Introduction Purpose Your goal is to create a design for a software interface. You will experience...
Introduction Purpose Your goal is to create a design for a software interface. You will experience the scope of the design process from brainstorming ideas and gathering information about users’ needs to storyboarding, prototyping, and finally, testing and refining your product. As you work on the software interface, you will demonstrate your ability to apply fundamental Human-Computer Interaction principles to interface analysis, design, and implementation. You will be responsible for delivering project components to your professor at several points during...
INTELLECTUAL PROPERTY  Industrial property forms part of the broader concept of "intellectual property."  The...
INTELLECTUAL PROPERTY  Industrial property forms part of the broader concept of "intellectual property."  The objects of intellectual property are the creations of the human mind, the human intellect hence the expression "intellectual" property.  In a somewhat simplified way, one can state that intellectual property relates to pieces of information which can be incorporated in tangible objects at the same time in an unlimited number of copies at different locations anywhere in the world.  The property is...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...
1. Which of the following in not directly involved in the production of proteins? a. Golgi...
1. Which of the following in not directly involved in the production of proteins? a. Golgi complex b. Plasma membrane c. Rough endoplasmic reticulum d. Nucleus 2. A new coach tells his team that the reason they get fatigued after three minutes of exercise is because they do not have enough oxygen in their red blood cells. He has no data to support his position. Therefore his advice is? a. Valid since he is an expert working with people b....
As you saw from the lab PowerPoint slides last week, you will be doing a research...
As you saw from the lab PowerPoint slides last week, you will be doing a research study looking at ‘Aggression Priming” for your first paper. For this week’s discussion, I want you to discuss with your group what you think this study is about. What is the hypothesis? What theory does it come from? What do you predict will happen (do you expect something different than the hypothesis in the researcher instructions? If so, what and why?)? Do you think...
It had been a busy day for Marsha Chamberland. She had spent most of it cleaning...
It had been a busy day for Marsha Chamberland. She had spent most of it cleaning and running errands in prepara- tion for her brother-in-law Ed’s return, and now she was preparing a quick dinner for her family. Ed, an industry official whose job it was to decide whether or not new products needed premarket approval by the U.S. Food and Drug Administration, had spent the last two weeks in Tennessee expressing his views on genetic engineering in food. He...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT