Question

What molecular signal is responsible for the survival of the cortical dendritic terminals?

Answer 1

Solution:

For the survival of cortical dentritic terminals, thalamus derived factors are involved. Thalamus derived factors or neurooeptides such as VGF and Neuritin -1 were found actively involved in the promotion of dendritic growth. The genes that encode Neuritin-1 is expressed for the post mitotic dufferentiation of neurons and associated structures . The VGF is neuropeptide which is secreted through ER mediated pathway. They are actively involved in maintaining synaptic maintenance.