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Frog Development. Explain the connection between the sperm’s introduction of the centriole and the formation of...

Frog Development.

Explain the connection between the sperm’s introduction of the centriole and the formation of the “Organizer”. Include molecular details!

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Answer #1

Sperm entry marks the ventral side of the embryo, the point opposite the sperm entry marks the dorsal side which later develop into the organiser ...sperm entry cause cortical cytoplasm to rotate ..this rotation brings the Disheveled protein and the GBP protein to the dorsal side from the vegetal side of the embryo. These Dsh/ GBP inhibits GSK3 protein ( an inhibitor of beta-catenin) this action activates the beta-catenin and through series of signaling processes this beta-catenin induces the organiser development.

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