Question

describe how B-cells and T-cells get activated in the adaptive immune response

Answer 1

When macrophage comes across an microbe the self and non-self protein recognizes the antigen. The self protein then forms complex with microbial antigen called as self-nonself complex. The antigen carrying macrophage then binds to the antigen binding site of helper-T cells via T-cell receptor. Here interleukin-I stimulated the helper-T cells. Once the macrophage carying ntigen binds and activated the helper-T cells interleukin-ii stimulates cell division and also activates other B and T cells. This is followed by secretion of antibodies by plasma cells by B cells. At last cytotoxic T cells attack on infected cells.