Draw a f
low chart to describe the innate and adaptive immune defenses provided when a
human host is exposed to a bacterial pathogen. Be sure to discuss phagocytes, the
complement system (
both
systems are activated here), TLRs, inflammation, APC, Th cells, B
cells, plasma cells, memory cells, antibody’s an
d their effector functions, MHC
. Make an effort
to include all of the activation signals and cytokines when possible.
The system of innate immune is a former and multiple defenses collection, comprising the pathogens identification through the pathogen receptors encoded by germline. The adaptive immune system, incorporating T and B cell responses, is a more current development which employs somatically recombined gene for receptor of antigen to identifies virtually any antigen. The benefits of adaptive immune system is the flexibility as well as immunologic memory but it is absolutely dependent upon innate immune system's element for the initiation as well as direction of responses. Accurate interactions of innate and acquired immune system result into highly productive recognition and pathogens clearance.
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