Question

What would happen to transport into and out of nuclei if Ran-GTP very rapidly degraded into...

What would happen to transport into and out of nuclei if Ran-GTP very rapidly degraded into Ran-GDP? What would happen if Ran-GTP could not be converted into Ran-GDP? Please explain your answers.

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Ans:- Ran is Ras related nuclear protein (protein of Ras family) involved in transport of protein and RNA during mitosis. inside nucleus Ran GDP converted to Ran GTP by C.C. (regulator of chromosome condensation 1) which is then transported to cytoplasm of cell where Ran GTP get converted in Ran GDP by Ran GAP (Ran GTPase activating factor) and Ran BP1 (Ran binding protein). if Ran GTP degrade very rapidly it will disrupt protein and RNA transport. different concentration of RCC1 and Ran GAP lead hight Ran GTP concentration inside and low Ran GTP Concentration outside of nucleus. if Ran GTP could not be converted into Ran GDP it will increase Ran GTP concentration outside nucleus which disrupt normal ration of Ran GTP and Ran GDP in and out side of nucleus. this disruption in Ran GTP and Ran GDP ratio will interfere in mitosis process of cell cycle.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
1-The transport receptor, exportin, functions to transport: a)RNA to the nucleus when associated with GDP-bound Ran...
1-The transport receptor, exportin, functions to transport: a)RNA to the nucleus when associated with GDP-bound Ran protein. b)RNA to the cytoplasm when associated with GTP-bound Ran protein. c)RNA to the cytoplasm when associated with GDP-bound Ran protein. d)RNA to the nucleus when associated with GDP-bound RNA protein. 2-Which of the following is not true regarding mRNA splicing and mRNA export from the nucleus? a)Spliced mRNA are exported with the assistance of the Ran pathway. b)All of the given answers are...
With regards to nuclear import, what would happen if there was a mutation in the Ran...
With regards to nuclear import, what would happen if there was a mutation in the Ran gene where its protein binds GDP irreversibly?
What would happen to the SA node if a chemical blocker was used to reduce transport...
What would happen to the SA node if a chemical blocker was used to reduce transport of Na+ into the pacemaker cells? What would happen to the SA node if a chemical blocker was used to reduce transport of Na+ into the pacemaker cells? There will be no change. The SA node would depolarize more slowly, increasing the heart rate. The SA node would depolarize more slowly, reducing the heart rate. The SA node would depolarize more quickly, increasing the...
4. Imagine a G-protein linked receptor that responds to an external signal that tells the cell...
4. Imagine a G-protein linked receptor that responds to an external signal that tells the cell to undergo cell division. Suppose that there is a mutation so that the G-protein linked to this receptor is unable to degrade the GTP attached to it to GDP. (That is, once the G-protein is bound to GTP, it stays that way, instead of converting the GTP to GDP after time has passed.) What would you predict would happen in the cell? Do you...
What would happen if atmospheric air pressure were to suddenly drop? Select one: a. CO2 would...
What would happen if atmospheric air pressure were to suddenly drop? Select one: a. CO2 would no longer flow out of your lungs b. Oxygen would flow into your lungs more quickly c. Oxygen would flow out of your lungs very quickly
if you were suddenly very frightened what would happen to your free fatty acids level and...
if you were suddenly very frightened what would happen to your free fatty acids level and why?
Please answer all parts. A.) GTP-bound G-protein will interact with an effector molecule. Name two effector...
Please answer all parts. A.) GTP-bound G-protein will interact with an effector molecule. Name two effector molecules. What change occurs in the GTP once effector interaction occurs? B.) Phosphorylation of GPCR (by GRK) results in binding sites for what molecule? What happens to the receptor at this point? C.) Trimeric protein reforms in this part (what is the state of the guanine nucleotide (GTP or GDP)? How would a non-hydrolyzable GTP influence this signalling? What about if only GDP was...
Explain what would happen if you did not filter out all the drying agent? Explain why...
Explain what would happen if you did not filter out all the drying agent? Explain why your melting point is lower than the accepted melting point? Explain how to calculate the solubility of a sustance (ex caffeine) in water and other solvents. What is meant by a partition coefficient of caffeine and water? How is it calculated?
What would happen to a cell if it did not contain carbohydrate chains? would this be...
What would happen to a cell if it did not contain carbohydrate chains? would this be fatal for an organism? please explain with examples.
What would happen specifically to metabolic pathways and cofactors, etc, involved if the levels/abilities of the...
What would happen specifically to metabolic pathways and cofactors, etc, involved if the levels/abilities of the glycolytic enzyme, GAPDH, were depleted? like for example I know that Krebs cycle could no longer continue since glucose can no longer be converted to pyruvate and then to acetyl-CoA. What else would be affected? what would increase and decrease?
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT