Question

Explain the relationship between the variable number of tandem repeats in the insulin promoter (Class I versus Class III VNTR) and genetic susceptibility to autoimmune diabetes

(Immunological response type 5 sentences max)

Answer 1

There is a great the relationship between the variable number of tandem repeats in the insulin promoter (Class I versus Class III VNTR) and genetic susceptibility to autoimmune diabetes. It is a long cencept but on your request i will explain its immunological response in less sentences.

Basic resaon behind that is insulin producing panecreatic B-cells.

Insulin genes are possed by thymus of human being which diectly response against diabetic cells.

Protective insuline mRNA play a measure role in immune system.

Higher binding sites also a big reason behind it overall process.

Tendems repeats in autoimmune system is approximatly by 1:3 which is scientifically proved.