Question

what is the role of tumor infiltrating lymphocytes [TIL] in patient prognosis

what is the role of tumor infiltrating lymphocytes [TIL] in patient prognosis

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Tumors antigens elicit an immune response in the host and this results in the infiltration of tumor infiltrating lymphocytes (TIL) to tumors. TILs include T-helper cells, T-cytotoxic cells, natural killer cells, B-lymphocytes, and macrophages.TheseTILs interact with tumor cells and eliminate them. However some tumor cells become resistant to TILs and escape immune detection or destruction. Presence of TILs is an indication of better prognosis and response to therapy for tumors.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Besides the existence of tumor-specific T cells and B cells, many studies have demonstrated that high...
Besides the existence of tumor-specific T cells and B cells, many studies have demonstrated that high numbers of tumor-infiltrating lymphocytes are associated with good clinical outcome. In addition, not only the density but also the organization of tumor-infiltrating immune cells has been shown to determine cancer patient survival. Indeed, more and more studies describe the development within the tumor microenvironment of this anatomic micro-structure, whose presence has a positive impact on tumor prognosis. What is it?
Ovarian cancer patients whose tumors had large numbers of infiltrating lymphocytes had a high rate of...
Ovarian cancer patients whose tumors had large numbers of infiltrating lymphocytes had a high rate of recurrence after the tumor removed relative to those tumors that lacked infiltrated lymphocytes. A)  True     B)  False
One important role of Fas and Fas ligand is to mediate the elimination of tumor cells...
One important role of Fas and Fas ligand is to mediate the elimination of tumor cells by killer lymphocytes. In a study of 35 primary lung and colon tumors, half the tumors were found to have amplified and overexpressed a gene for a secreted protein that binds to Fas ligand. How do you suppose that overexpression of this protein might contribute to the survival of these tumor cells? Explain your reasoning.
make up a stage 3 copd patient prognosis. and give general prognosis information as well. short.
make up a stage 3 copd patient prognosis. and give general prognosis information as well. short.
what is the role of protooncogenes and tumor suppressor genes in normal cell cycle regulation and...
what is the role of protooncogenes and tumor suppressor genes in normal cell cycle regulation and cancer ?
There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that...
There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that they can be harnessed to use the body's immune system to treat cancer. One study investigated the use of a T cell-engaging antibody, blinatumomab, to recruit T cells to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study) and after 20 days on blinatumomab for 6 subjects in the study. The difference (after 20...
There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that...
There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that they can be harnessed to use the body's immune system to treat cancer. One study investigated the use of a T cell-engaging antibody, blinatumomab, to recruit T cells to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study) and after 20 days on blinatumomab for 6 subjects in the study. The difference (after 20...
2. Provide the definition for oncogene and tumor suppressor gene. What role do these both play...
2. Provide the definition for oncogene and tumor suppressor gene. What role do these both play regarding cancerous cells? (Provide 3 to 5 sentences)
. A patient is diagnosed with lung cancer. The biopsy sample form the tumor shows that...
. A patient is diagnosed with lung cancer. The biopsy sample form the tumor shows that the tumor is p53 mutant, but the peripheral blood DNA contains wild type DNA. Please discuss the outcome of radiotherapy for this patient
Describe the role of TAM [tumor associated macrophages] in comparison to regular macrophages
Describe the role of TAM [tumor associated macrophages] in comparison to regular macrophages
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT