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why can't lactose go through fermentation with yeast but sucrose and glucose can?

why can't lactose go through fermentation with yeast but sucrose and glucose can?

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Yeast (Saccharomyces cerevisiae) cannot ferment lactose as they lack the lactose permease and beta galactosidase enzyme. The lactose permease enzyme allows lactose to enter the cell. Beta galactosidase ferments lactose and breaks down the beta glycosidic bonds (beta 1,4) between galactose and glucose. If pre-hydrolysed lactose is used, it will cause glucose repression of galactose metabolism.

Yeast however, have the sucrase and invertase enzymes that can break down sucrose to glucose and fructose. Glucose and fructose are then fermented to form alcohol and carbon dioxide. Thus, Yeast can ferment sucrose to form ethanol and carbon dioxide.

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