Uterine gland morphogenesis during pregnancy allows for the endometrium to increase output of secretory proteins that are transported to the fetus by specialized areas of the placenta termed areolae, which provide histotrophic nutrition to the fetus throughout pregnancy.
Histotrophic nutrition:The endometrium contains extensive uterine glands that synthesize and secrete substances into the uterine lumen, including a complex array of enzymes, growth factors, cytokines, lymphokines, hormones, transport proteins and other substances, collectively termed histotroph.
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