Question

1. What is the difference between sickle-cell trait and sickle-cell disease:

1. sickle-cell disease life expectancy = 40 years
2. only people of African decent can get sickle cell disease
3. only people with sickle-cell disease have sickled RBCs
4. people with sickle-cell disease are immune to malaria

2. Which of the following individuals, residing in Sub-Saharan Africa, is least likely die from a malarial infection:

1. HgbAA
2. HgbAS
3. HgbSS

Answer 1

Answer:

• D. people with sickle-cell disease are immune to malaria

Sickle cell Disease provides resistance against malaria. Other options are incorrect as:

It may be found in other area other than Africa.

Even Sickle cell trait patients have some sickled blood cell.

Life expectancy is around 42-48 years or higher.

• C. HgbSS

They are most resistant to malaria. So people are least likely to die from malaria.

Other options are incorrect as HgbAS are somewhat resistant to malaria. HgbAA is the least resistant .