Question

A widow’s peak is an autosomal dominant trait while a straight hairline is a recessive trait....

  1. A widow’s peak is an autosomal dominant trait while a straight hairline is a recessive trait. Mike and his dad have a widow’s peak. Mike marries Bethany who has a continuous hairline like Mike’s mom. What is the probability that Mike and Bethany’s first child will have a widow’s peak? Complete Punnett Square to support your answer.

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Probability of first child:

A 15-year old boy was diagnosed with a usual autosomal inherited form of diabetes. His mother was diagnosed with the same form of diabetes at 15, but his father is not a carrier.

  1. What is pattern of inheritance for this form of diabetes – autosomal dominant, autosomal recessive, sex-linked dominant, sex-linked recessive?

Use the Punnett Square to determine the probability that the second boy in the family will be diagnosed with diabetes when he comes of age.

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Probability of diagnosis:

Sickle cell anemia (SCA) is a condition exhibit by homozygous recessive individuals resulting in a sickle shape of red blood cells reducing the oxygen supply throughout the body. Without proper treatment, the disease can be fatal. Individuals that are carriers are said to have sickle cell trait (SCT). This disease is prevalent in Africa, and individuals of African decent, due to protection sickle cells provide against malaria.

  1. What is pattern of inheritance for this form of diabetes – autosomal dominant, autosomal recessive, sex-linked dominant, sex-linked recessive?
  1. A SCT female has a child with a SCA male. Write the possible genotypes and phenotypes of offspring with percent. Use the terms homozygous dominant, homozygous recessive, and heterozygous for genotypes with allele letters. Phenotypes terms - normal, SCT, SCA. You do not have to show Punnett Square.

Genotypes:

Phenotypes:

A muscle degenerative condition (MDC) is inherited by individuals with two copies of the allele that is located on the X of chromosome 23. The condition leads to degeneration of muscle tissue throughout the body.

  1. What is pattern of inheritance for this form of diabetes – autosomal dominant, autosomal recessive, sex-linked dominant, sex-linked recessive?

A husband with the condition has a child with a normal woman. Use the Punnett Square and write the possible genotypes and phenotypes of each sex with percent. Use the terms homozygous dominant, homozygous recessive, and heterozygous for genotypes with allele letters. Phenotypes terms - normal, MDC.

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Male Genotypes:

Male Phenotypes:

Female Genotypes:

Female Phenotypes:

  1. Can a child inherit a sex-linked condition from two parents that are phenotypic normal? Explain.

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