After intracellular proteins are damaged, heat shock factors serve to increase the amount of heat shock proteins, which translocate to the damaged protein and replace damaged amino acids with new amino acids.
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Heat shock proteins are a family of proteins that are produced by cells in response to exposure to stressful conditions. During heat stress, outer membrane proteins do not fold and cannot insert correctly into the outer membrane. They accumulate in the periplasmic space. The increase in damaged, or abnormal proteins brings HCPs in to action.
Under stressful conditions such as heat shock or hypoxia, increased expression of heat shock proteins protect the cells by stabilising unfolded or misfolded peptides. It thereby gives the cell the time to repair or resynthesize damaged protein.
Therefore the statement is true
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