A doctor wants to estimate the mean HDL cholesterol of all 20- to 29-year-old females. How many subjects are needed to estimate the mean HDL cholesterol within
4 points with 99% confidence assuming s=14.3 based on earlier studies? Suppose the doctor would be content with 95% confidence. How does the decrease in confidence affect the sample size required?
Solution :
Given that,
standard deviation = S = 14.3
margin of error = E = 4
a ) At 99% confidence level the z is ,
= 1 - 99% = 1 - 0.99 = 0.01
/ 2 = 0.01 / 2 = 0.005
Z/2 = Z0.005 = 2.576
Sample size = n = ((Z/2 * S) / E)2
= ((2.576 * 14.3 ) / 4 )2
= 85
Sample size = 85
b ) At 95% confidence level the z is ,
= 1 - 95% = 1 - 0.95 = 0.05
/ 2 = 0.05 / 2 = 0.025
Z/2 = Z0.025 = 1.960
Sample size = n = ((Z/2 * S) / E)2
= ((1.960 * 14.3 ) / 4 )2
= 49
Sample size = 49
c ) The decrease in confidence level decrease in sample size.
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