A doctor wants to estimate the mean HDL cholesterol of all 20- to 29-year-old females. How many subjects are needed to estimate the mean HDL cholesterol within 33 points with 99 %99% confidence assuming s equals 11.2s=11.2 based on earlier studies? Suppose the doctor would be content with 95 %95% confidence. How does the decrease in confidence affect the sample size required? A 99% confidence level requires ____subjects. A 95% confidence level requires ____subjects.
Solution:- Given that s = 11.2, E = 3
95% confidence interval
The critical value corresponding to the given situation is obtained
as Z(α/2) = 1.96
1 - α = 1 - 0.95
α = 0.05
α/2 = 0.05/2 = 0.025
Z0.05 = 1.96
99% confidence interval
The critical value corresponding to the given situation is obtained
as Z(α/2) = 2.576
1 - α = 1 - 0.99
α = 0.01
α/2 = 0.01/2 = 0.005
Z0.005 = 2.576
A 99% confidence level requires 93 subjects
n = (Z*S/E)^2 = (2.576*11.2/3)^2 = 92.487 = 93
A 95% confidence level requires 54 subjects
n = (Z*S/E)^2 = (1.96*11.2/3)^2 = 53.543 = 54
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