Question

The Physicians' Health Study randomly assigned 22,071 healthy male physicians at least 40 years old to...

The Physicians' Health Study randomly assigned 22,071 healthy male physicians at least 40 years old to take either an aspirin every other day or a placebo pill every other day. Of the 10825 physicians who took aspirin regularly for 5 years, 13 had a fatal heart attack and 131 had a nonfatal heart attack. Of the 11246 who took the placebo, 26 suffered a fatal heart attack and 223 had a nonfatal heart attack. Please use 4 decimal places to answer the questions below.

(a) What is the proportion of physicians who suffered a fatal heart attack in the: aspirin group? placebo group? (Answers = .001 and .0023)

(b) Calculate the relative risk of a fatal heart attack for physicians taking aspirin compared with those taking a placebo (do not use the rounded values from part (a) to do your calculations. Use the original proportions in your calculation. Remember, give your answer to 4 decimal places.). (NOTE* the answer is NOT .4347)

(c) What is the proportion of physicians who suffered a nonfatal heart attack in the: aspirin group? placebo group? (Answers = .0121 and .0198)

(d) Calculate the relative risk of a nonfatal heart attack, for physicians taking aspirin compared with those taking a placebo (do not use rounded values in your calculation and give your answer to 4 decimal places). (NOTE* the answer is NOT .6111)

Homework Answers

Answer #1

(a) proportion of physicians who suffered fatal heart attack in aspirin group = 13/10825= 0.0012

proportion of physicians who suffered fatal heart attack in placebo group = 26/11246= 0.0023

(b) relative risk of fatal heart attack = (13/10825) / (26/11246) = 0.5194

(c) proportion of physicians who suffered nonfatal heart attack in aspirin group = 131/10825 = 0.0121

proportion of physicians who suffered nonfatal heart attack in placebo group = 223/11246 = 0.0198

(d) relative risk of nonfatal heart attack= (131/10825) / (223/11246) = 0.61029

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