The Physicians' Health Study randomly assigned 22,071 healthy male physicians at least 40 years old to take either an aspirin every other day or a placebo pill every other day. Of the 10825 physicians who took aspirin regularly for 5 years, 13 had a fatal heart attack and 131 had a nonfatal heart attack. Of the 11246 who took the placebo, 26 suffered a fatal heart attack and 223 had a nonfatal heart attack. Please use 4 decimal places to answer the questions below.
(a) What is the proportion of physicians who suffered a fatal heart attack in the: aspirin group? placebo group? (Answers = .001 and .0023)
(b) Calculate the relative risk of a fatal heart attack for physicians taking aspirin compared with those taking a placebo (do not use the rounded values from part (a) to do your calculations. Use the original proportions in your calculation. Remember, give your answer to 4 decimal places.). (NOTE* the answer is NOT .4347)
(c) What is the proportion of physicians who suffered a nonfatal heart attack in the: aspirin group? placebo group? (Answers = .0121 and .0198)
(d) Calculate the relative risk of a nonfatal heart attack, for physicians taking aspirin compared with those taking a placebo (do not use rounded values in your calculation and give your answer to 4 decimal places). (NOTE* the answer is NOT .6111)
(a) proportion of physicians who suffered fatal heart attack in aspirin group = 13/10825= 0.0012
proportion of physicians who suffered fatal heart attack in placebo group = 26/11246= 0.0023
(b) relative risk of fatal heart attack = (13/10825) / (26/11246) = 0.5194
(c) proportion of physicians who suffered nonfatal heart attack in aspirin group = 131/10825 = 0.0121
proportion of physicians who suffered nonfatal heart attack in placebo group = 223/11246 = 0.0198
(d) relative risk of nonfatal heart attack= (131/10825) / (223/11246) = 0.61029
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