What is the difference between the muscle relaxants dantrolene and baclofen?
Dantrolene | Baclofen |
It is a post synaptic muscle relaxant | It is a CNS depressant |
It is administered intravenously | It is administered intrathecally, orally and topically |
It decreases excitation contraction | it acts on skeletal muscle |
Inhibits calcium ions | doesn't inhibits Ca ions |
Metabolised in liver |
metabolised by destinationn |
Excreted by biliary and renal tracts. | Excreted by renal system |
Used in malignant hyperthermia,anesthetic allergies | used on alcohol withdrawal symptoms |
Restricted with renal and liver impairments,CVD | used in multiple sclerosis |
Children below 5 year can't be given | can't be indicated for stroke and Parkinson patient |
Get Answers For Free
Most questions answered within 1 hours.