Question

What is the difference between the muscle relaxants dantrolene and baclofen?

What is the difference between the muscle relaxants dantrolene and baclofen?

Homework Answers

Answer #1
Dantrolene Baclofen
It is a post synaptic muscle relaxant It is a CNS depressant
It is administered intravenously It is administered intrathecally, orally and topically
It decreases excitation contraction it acts on skeletal muscle
Inhibits calcium ions doesn't inhibits Ca ions
Metabolised in liver

metabolised by destinationn

Excreted by biliary and renal tracts. Excreted by renal system
Used in malignant hyperthermia,anesthetic allergies used on alcohol withdrawal symptoms
Restricted with renal and liver impairments,CVD used in multiple sclerosis
Children below 5 year can't be given can't be indicated for stroke and Parkinson patient
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