Question

Find an antibiotic that targets some aspect of TRANSCRIPTION in PROKARYOTIC organisms. For the antibiotic you have selected, provide the information requested below.

Name of antibiotic:

Class of antibiotic

: Process targeted/affected by the antibiotic [What step/process in transcription is impaired?]:

Specificity [which organisms is it effective against]: Mechanism of action [how does it kill the organism or impair growth of the organism?]:

Source[s] of information [Provide complete URL(s) and/ or bibliographic reference(s)]:

Answer 1

Strptomycin is a common antibiotic which has effect up on the prokaryotic organisms.

Name of the antibiotic: Streptomycin

Class of antibiotic: Aminoglycosides

Organisms for which streptomycin effective; Streptomycin is a powerful antibiotic effective against mycobacterium tuberculosis, plague, brucellosis, entero cocci, Y. pestis, tularemia infection etc.

Mechanism of action: Streptomycin mainly works by binding to the specific prokaryotic bacterial ribosomal unit, after that the drug will cause misreading of Transfer RNA. This will cause the bacterium tunable to synthesize proteins vital for its growth and functions. Thus the bacterium remail unable to functuon and loss its ability.This drug also inhibit the growth and development of both gram positive and gram negative organisms.