Question

true or false question

____ The most common form of penicillin resistance occurs when bacteria evolve an enzyme that cleaves penicillin.

____ Glucose and galactose are 4-anomers of each other.

____ When a ketohexose cyclizes, carbon 2’s oxygen becomes the ring oxygen.

Which statement is correct about the Michaelis-Menten constant, K​m,​ for the enzymatic reaction below? k​1​ k​2

E + S ​→​ ES ​→​ E + P

A. It is numerically equal to the velocity that is one half the maximum velocity.
B. Its numeric value has the units of “moles product per minute”.
C. It is approximately equal to the dissociation constant for the enzyme-substrate complex to E + P. D. It is defined as K​m​ = 0.5( V​max)​
E. None of the above statements are true.

2. All of the following statements are true about the relationships between [S], K​m​ and V​max​ EXCEPT:

A. As the [S] is increased, v approaches the limiting value, V​max.​
B. K​m = the substrate concentration at which the velocity is V​max/2.
C. Therateofthereaction,v,changesas[S]changes.

D. The rate of product formation is at V​max​ when [S] >> K​m.​ E. When[S]=2(K​m)​ ,thevelocityhasreacheditsplateau.

Answer 1

1.False (This is a definitely a process of penicillin resistance but not most common,the most common form of resistance is gram +ve bacterias restrict the transport of penicillins to their cell wall)

2.False (Glucose and Galactose are C-4 epimers of eac other,Glucopyranose and Galactopyranose are anomers of each other as anomers are cyclic molecules)

3.False ( C5 oxygen becomes the ring oxygen,Mechanism below-)

4.Option A( Km is the concentration of enzyme which corresponds to one half the maximum Velocity vmax)

5.Option E.(The option 4 already says [S]>>Km).