Question

Where in the cell does fatty acid oxidation take place?

Where in the cell does fatty acid oxidation take place?

Homework Answers

Answer #1

inside the mitochondria fatty acid oxidation take place. general procesure given as below

  • most fat stored in eukaryotic organism as triglyceride with use of enzyme 'lipase' triglyceride break into glycerol molecule and three fatty acid
  • 'Acyl- CoA synthase' yield fatty acid to fatty acyl CoA before enter into mitochondria.
  • after fatty acid been acylated it is ready to enter into mitochondria
  • there are two carrier protein 'carnitine acyl transferase I and II' one located outer membrane and one located inner membrane of mitochondria both help for entry of acyl CoA into mitochondria.
  • once inside mitochondria the fatty acid -CoA can enter into beta oxidation.
  • Beta oxidation of fatty acid take place into mitochondria and cleaved acyl CoA formed inter into TCA and ETC because it is allready whithin mitochondria.
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