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What are the effects of activation of the following receptors? Kindly include the organ-specific effects and...

What are the effects of activation of the following receptors? Kindly include the organ-specific effects and all drugs that agonize and antagonize these receptors.

Alpha-1, alpha-2, beta-1, beta-2, acetylcholine (nicotinic-M, muscarinic)

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Answer #1

Alpha-1 receptor: Blood vessels with this receptor are present in kidney, GIT, skin, Brain. It causes vasoconstriction.

salivary glands secretion increases, Na reabsorption from kidney.

Agonists: Methoxamine, Phenylephrine.

Antagonist: Prazosin , terazosin

Alpha-2: Decreased secretion from salivary glands, Relax GIT, decreases motility of smooth muscles.

Agonist: Clonidine, Imidazole

Antagonist: Yohimbine, Phentolamine.

Beta-1: Relaxation of brinchial smooth muscles, stimulate renin release from kidney

Agonist: Dobutamine

Antagonist: Atenolol

Beta-2:Dilatation of Bronchial passage, relaxation of uterine muscle

agonist: Alupent

Antagonist: Propranolol

Acetylcholine receptor:

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