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Histones are proteins that function in compacting DNA. They have DNA wrap tightly around them. Histones...

Histones are proteins that function in compacting DNA. They have DNA wrap tightly around them. Histones have more positive charges than a normal protein. This is not by accident. The positive charges help them function. What is the reason for this? Explain your answer!

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Histones are positively charged proteins whereas the DNA molecules are negatively charged due to phosphate groups. This helps in tight packaging of the genetic material providing higher levels of organisation. The opposite charges of both the molecules exhibit stronger electrostatic interactions between them . If histones were also like charged (negatively) as DNA molecule , they would repel each other , instead of binding it , which would prevent them to perform their function DNA regulation and transcription.

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