Question

What is the best choice of a variable molecular marker for investigating gene flow between populations...

What is the best choice of a variable molecular marker for investigating gene flow between populations of squirrels that were geographically separated but recently brought back together by looking for exchanges of population-specific variants in the molecular markers?

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Answer #1

Answer: SNPs in DNA and Microsatellites in DNA

Solution: SNPs (single nucleotide polymorphisms), which belong to the last generation molecular markers, occur at high frequencies in both animal and plant genomes. The development of SNP markers allows to automatize and enhance tenfolds the effectiveness of genotype analysis.

Microsatellite markers are co-dominant, polymorphic DNA loci containing repeated nucleotide sequences, typically with 2 to 10 nucleotides per repeated unit.

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