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We know that red blood cells are eliminated in the spleen thanks to macrophages. But what...

We know that red blood cells are eliminated in the spleen thanks to macrophages. But what about old or malfunctioning white blood cells? Do they simply die in the bloodstream or is there a specialized organ for their elimination?
Thanks in advance!

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Answer #1

ANSWER:

Dead white blood cells are removed from circulation by the macrophages in the spleen.

EXPLANATION:

The spleen forms antibodies in its white pulp m that removes antibody-coated bacteria and antibody-coated blood cells through blood and lymph node circulation.

Macrophages remove dead cells by eating them.

White blood cells programmed to die an apoptotic death after few days. These dead cells may continue to flow through the body bloodstream or collect in various organs such as spleen.

Macrophages in the spleen phagocytize the worn out RBCs. The heme and globin portions are split apart.

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