When glycerol is the precursor for gluconeogenesis only one reaction requires ATP. Describe this reaction and explain why 2 ATP molecules are consumed.
Gluconeogenesis is the production of carbohydrates from non carbohydrate precursors. Glycerol is component of lipids but it can bu utilized to make carbohydrates. Glycerol is formed by the hydrolysis of triglycerides and are transported to hepatocytes by passive transport. Inside the hepatocytes, glycerol is converted to glycerol 3-phosphate with the help of the enzyme Glycerolkinase. During this time ATP molecule is hydrolyzed and form ADP and the phosphate group is incorporated in Glycerol to form Glycerol 3-phosphate.
Glycerol +ATP ------------------------Glycerol 3-phosphate + ADP, enzyme - Glycerolkinase
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