Question

Among the genetic damage to the DNA, what is the one which is easily reparable?

1. Single-strand break (SSD):

2. Double strand break (DSB):

3. Deletions

4. Nitrogen base pairing damage

Answer 1

Single stranded break is easily repairable because it need only those enzymes which are employed in normal replication.

Double stranded break repair is more difficult than single strand because it involves recombination.

Dletions are also most difficult because once a nucleotide is lost from the DNA sequence they cannot be added there again.

Nitrogen base pairing damage difficult than single strand break it involves removal of the base, then sugar and then finally addition of new nucleotides.

It involves enzymes which are not part of normal DNA replication.