Question

A strategy common to treating bacterial infections and cancer is to provide patients with two different antibiotics (for infections) or two different chemotherapeutic agents (for cancer) using two drugs that act on two distinct targets. This strategy is aimed at reducing complications from bacteria or cancer cells developing resistance to the drugs. What is the general notion behind this strategy? I.e., exactly why could one expect the chance for developing resistance to be much less?

Answer 1

Question

When more than one antibiotics are used to treat bacterial infection and more than 1 chemotherapeutic agent is use to treat cancer is known as combination therapy. The function of combination therapy are :

I. Using more than 1 antibiotics increases broadens the antibacterial spectrum. This will ensure that at least one antibiotic will cover the disease completely.

II. Chance of reemergence of resistance against two drugs is very less as compare to using one drug only.

III. Combination therapy will provide more synergistic action. This Synergistic activity is used to combat infection more effectively.