Question

Which enzyme does NOT use glyceraldehyde-3-phosphate as a substrate or product?

triose phosphate isomerase

phosphoglycerate mutase

aldolase

glyceraldehyde-3-phosphate dehydrogenase

Answer 1

Glycolysis is the oxidative process in which glucose is broken down in a series of enzyme catalysed reactions. It is a 10 step process.

In the 4th step, when glyceraldehyde-3-phosphate (G3P) is formed from fructose-1,6-bisphosphate with the help of Aldolase (G3P as product).

G3P is converted to dihydroxyacetone phosphate by Triose phosphate isomerase ( it uses G3P as substrate).

G3P is converted to 1,3- bisphosphoglycerate in 6th step by G3P Dehydrogenase. (G3P as substrate).

Correct answer is Phosphoglycerate mutase that doesn't use G3P as substrate or a product. Because this converts 3PG to 2 PG. (2-phosphoglycerate).