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Describe two examples OF COMPONENTS of the 1st line of defense that interact woth or communicate...

Describe two examples OF COMPONENTS of the 1st line of defense that interact woth or communicate with the 3rd line of defense...

i do not need am explanation Of what the 1st or 3rd line of defenses are, I NEED TO KNOW THE COMPONENTS IN 1st LINE THAT COMMUNICATE WITH THE 3rd LINE!
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Ans . Neutrophils and Macrophages are the two examples of components of the 1st line of defense that interact with or communicate with the 3rd line of defense.

The third line of defense is specific resistance. This system relies on antigens, which are specific substance found in foreign microbes. The activation of T- cells by a specific antigen is called cell-mediated immunity.

Macrophage is the first cell to recognize and engulf foreign substances (antigens). Macrophages breakdown these substances and present the smaller proteins to the T-lymphocytes.

Neutrophils negatively influence CD4+ T cells as well as the interaction between some immune cells to supress the immune response.

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