Question

Account for the total and net yield of ATP from 1-molecule of Arachidonic acid. FA activation...

Account for the total and net yield of ATP from 1-molecule of Arachidonic acid.

FA activation =

Oxidation of Acetyl CoA (in the TCA)= show the detailed math

Oxidation of FADH2 = show the detailed math

Oxidation of NADH= show the detailed math

What else? show the detailed math

What else? show the detailed math

Total yield= show the detailed math

Net? show the detailed math

How many sucrose units will it take to approximately match the energy yield of arachidonic acid using the glycerol phosphate pathway?

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Homework Answers

Answer #1

Total yield of ATP from 1 molecule of Arachidonic acid.

FA activation = -2 ATP

Oxidation of Acetyl CoA (in the TCA)= Arachidonic acid has 20 carbons, it undergoes 9 cycles of beta oxidation. 9 cycles give 10 acetyl CoA molecules and one acetyl CoA give 10 ATP in TCA cycle. so 10 Acetyl CoA gives =100 ATP

Oxidation of FADH2= during beta oxidation 9 NADH and 9 FADH2 are produced. I FADH2 gives 1.5 ATP so 9 FADH2 gives=13.5 ATP

Oxidation of NADH= 2.5x9= 22.5 ATP

This gives a total of 136 ATP and 2 ATP are used for the process of activation. so total yield of ATP-=134 ATP.

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