. Suppose you start with 1 molecule of glucose and go through glycolysis to produce 2 molecules of pyruvate. These 2 molecules of pyruvate are then converted into acetyl CoA which then go through the TCA cycle. Approximately how many total ATP / ATP-equivalents can be formed through this process? (Account for NADH/FADH2 produced). Show where each molecule of ATP is generated from.
#Energy gain (ATP)/glucose in glycolysis under aerobic condition:
Rea 3(PFK)-1 ATP
Rea 6(G 3-PDH)-2.5*2=5
#Energy gained in TCA
isocitrate DH 2.5*2=5 ATP
ketoglutarate DH 2.5*2=5 ATP
S.thiokinase 1*2=2 ATP
S. DH 1.5*2=3 ATP
Malate DH 2.5*2=5 ATP
#Net ATP generation in glycolysis 9-2=7 ATP
ATP generation in PDH 2.5*2=5 ATP
ATP generation in citric acid cycle 20 ATP
therefore net generation of ATP from one glucose molecule= 32 ATP
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