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Uridylylation of PII stimulates the formation of glutamine from glutamate. True or False?

Uridylylation of PII stimulates the formation of glutamine from glutamate. True or False?

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Ques: Uridylylation of PII stimulates the formation of glutamine from glutamate. True or False?

True.

Glutamine synthetase is an enzyme that catalyzes the conversion of Glutamate and  Ammonia into Glutamine. This enzyme is regulated by Adenyl transferase which in turn is regulated by a regulator protein PII. If PII is uridylylated, it forms a complex with the adenyl transferase and activates Glutamine Synthetase by deadenylation. If it is not uridylylated, then the complex deactivates Glutamine synthetase by adenylation.

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