Question

the events below are what happens when a G-protein coupled receptor is activated. Place the events...

the events below are what happens when a G-protein coupled receptor is activated. Place the events in the correct order.

-Conformational shift in the alpha subunit of the G protein
-Increase in the affinity of the receptor for a G protein on the cytoplasmic surface of the membrane.
-G protein binds to activated receptor forming a receptor-G protein complex
-Binding of a hormone to a G-protein couple receptor
-Dissociation of the Ga subunit and the GBy complex
-Release of GDP and binding of GTP by the G protein
-Change in conformation of the cytoplasmic loops of the receptor.

Homework Answers

Answer #1

series:

Increase in the affinity of the receptor for a G protein on the cytoplasmic surface of the membrane.

Binding of a hormone to a G-protein couple receptor

-G protein binds to activated receptor forming a receptor-G protein complex

Change in conformation of the cytoplasmic loops of the receptor.

Conformational shift in the alpha subunit of the G proteinConformational shift in the alpha subunit of the G protein

Release of GDP and binding of GTP by the G protein

Dissociation of the Ga subunit and the GBy complex

please do like the answer

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
When a hormone such as epinephrine binds to a GTP-bound receptor, the G protein alpha subunit...
When a hormone such as epinephrine binds to a GTP-bound receptor, the G protein alpha subunit leaves to activate adenylyl Cyclase. When the alpha subunit re-associates with the beta/gamma subunits of the G protein, is the hormone still attached to the GTP-bound receptor? When exactly does the hormone leave the receptor — is it when the G protein is GTP-activated or when the G protein is reassembled back into alpha/beta/gamma?
Acetylcholine binds to a G-coupled protein receptor on the heart muscle to make the heart beat...
Acetylcholine binds to a G-coupled protein receptor on the heart muscle to make the heart beat more slowly. It does so by stimulating the opening of K+ channels in the plasma membrane, which makes it more difficult to initiate and action potential. Describe the following on contraction of the heart. A.) Addition of a drug that inhibits the GTPase activity of the Ga subunit. B.) Mutations in the K+ channel that keep it closed all the tiem. C.) A mutation...
Describe in detail what happens in a gustatory cell when PTC binds the G-protein coupled receptor...
Describe in detail what happens in a gustatory cell when PTC binds the G-protein coupled receptor TAS2R38.
Which of the following statements about G-Protein Coupled Receptor (GPCR) signaling or Protein Kinase A (PKA)...
Which of the following statements about G-Protein Coupled Receptor (GPCR) signaling or Protein Kinase A (PKA) activation is correct? I. GPCR kinases phosphorylate GPCRs on their intracellular surface promoting the binding ofβ-Arrestin and the inhibition of GPCR signaling. II. The pseudosubstrate sequence located in the PKA regulatory domain binds to an AKAP protein in the absence of cAMP. III. The PKA catalytic and regulatory domains are part of a single polypeptide chain. IV. The slow hydrolase activity of the PKA...
Where is the G-protein complex when a ligand is not bound to its receptor? The beta...
Where is the G-protein complex when a ligand is not bound to its receptor? The beta and gamma subunits are attached to the inner surface of the receptor. The three subunits are together but not attached to the inner surface of the receptor. The alpha subunit is attached to the inner surface of the receptor. Which of the following does NOT affect the rate of diffusion through a membrane? membrane pore size solute size solute concentration solute kinetic energy The...
Please answer all parts. A.) GTP-bound G-protein will interact with an effector molecule. Name two effector...
Please answer all parts. A.) GTP-bound G-protein will interact with an effector molecule. Name two effector molecules. What change occurs in the GTP once effector interaction occurs? B.) Phosphorylation of GPCR (by GRK) results in binding sites for what molecule? What happens to the receptor at this point? C.) Trimeric protein reforms in this part (what is the state of the guanine nucleotide (GTP or GDP)? How would a non-hydrolyzable GTP influence this signalling? What about if only GDP was...
7.)In G proteins, which form of the guanyl nucleotide is bound in the unactivated state? a.)...
7.)In G proteins, which form of the guanyl nucleotide is bound in the unactivated state? a.) GTP b.) GDP c.) GMP d.) dGTP e.) None of above 8.)which of the following amino acids can be phophorylated? a.) tyrosine, serine, theronine b.) tyrosine, serine, tryptophan c.) serine, threonine, asparagine d.) histidine, serine, phenylalanine e.) tyrosine, methionine, typrtophan 9.) most signal molecules: a.)easily diffuse through the membrane and bind to a receptor in the cytoplasm b.) bind to membrane receptors and transmit...
1. Which sentence best defines signal transduction in a biochemical context? a. Alteration of cell functions...
1. Which sentence best defines signal transduction in a biochemical context? a. Alteration of cell functions in response to the environment b. Generation of a chemical change in response to information c. Induction of cell death upon nutrient starvation d. Responses to stimuli 2. Which statement is correct? a. G protein-coupled receptors produce second messengers indirectly while receptor enzymes catalyse second messenger generation b. Second messengers stimulate the activity of G protein-coupled receptors. c. Receptor enzymes produce second messengers through...
QUESTION 14 Given: Net Filtration Pressure = (PC – PIF) – (πC – πIF) IF: capillary...
QUESTION 14 Given: Net Filtration Pressure = (PC – PIF) – (πC – πIF) IF: capillary colloid osmotic pressure = +22 mmHg : interstitial fluid colloid osmotic pressure = +4 mmHg : capillary hydrostatic pressure = +30 mmHg : interstitial fluid hydrostatic pressure = -2 mmHg THEN, the Net Filtration Pressure is _____________ and there is _______________ across the capillary wall. a. -14 mmHg, Net Reabsorption b. 10 mmHg, Net Filtration c. None of the answers given here are correct...