Question

For each of the following true/false statements. Indicate if the statement is true or false. If...

For each of the following true/false statements. Indicate if the statement is true or false. If false, correct the statement to be true.

A. _____ Fas ligand binding with Fas receptor stimulates a specific G protein

B. _____ A mutation in Bax that blocks Bax binding to the mitochondria will promote apoptosis

C. _____ Telomerase activity is off in most somatic cells in adults

D. _____ The telomerase enzyme extends the telomeres using its RNA polymerase activity.

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Answer #1

A. False.

Fas ligand binding with Fas receptor doesn't stimulate a G protein. It stimulates caspase 8 via FADD.

B. False.

Binding of Bax to the mitochondrial membrane is important for apoptosis. So, any mutation in Bax that blocks it's binding to mitochondrial membrane would stop apoptosis.

C. True.

Telomerase activity is off in most somatic cells in adults. This helps aging process via gradual shortening of telomeres.

D. False.

Telomerase is an RNA-dependent DNA polymerase. It uses short RNA sequence as template to synthesize DNA.

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