Question

Answer true or false if the following statement/property is true about zinc fingers: 1. provide recognition...

Answer true or false if the following statement/property is true about zinc fingers:

1. provide recognition and binding between two response elements.

2. provide recognition and binding between a hormone receptor complex and response element.

3. coordinated by 4 cystine residues.

4. coordinated by 2 aspartate and 2 serine residues.

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Answer #1

Answer: Choices 1, 2

Reason: Zinc finger motifs are stabilized either by a pair of cystein and histidine or 6 cystein residues structurally. Further, aspartate and serine residues do not play role in stabilization of these motifs. Zinc fingers are recognition and transcription proteins which help in coordination between a protein receptor and its ligand in the cell where a membrane bound structure is present, such as plasma membrane as well as nuclear membrane.

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