Question

Describe the function of the SGLT-1 transporter. This transporter can transport glucose into cells (without using...

Describe the function of the SGLT-1 transporter. This transporter can transport glucose into cells (without using ATP) even if the concentration of glucose in the cell is lower than that outside. How is this possible?

Science   Anatomy-And-Physiology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Sodium dependent glucose cotransporter 1 or SGLT are present in small intestine and proximal renal tubules.
SGLT1 helps in reabsorption of glucose molecule through the tubules by binding to the glucose and transporting it back into the blood. SGLT1 functions to reabsorb the glucose present in glomerular filtrate and send it back to blood.
The Na/K ATPase pump in the basolateral membrane pumps 3 sodium ions into the blood in exchange for 1 potassium ion. This creates a concentration gradient. The SGLT1 transports the glucose across the membrane with the help of this concentration gradient created by Na/K ATPase pump. That is why SGLT1 can transport glucose into cells without using ATP even if the concentration of glucose in the cell is lower than that outside.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
A passive transporter is discovered that can transport both galactose and glucose. The pore of the...
A passive transporter is discovered that can transport both galactose and glucose. The pore of the transporter can accommodate a single sugar at a time. If the extracellular concentrations of galactose and glucose are 0.25 and 4.0 mM, respectively, and the intracellular concentrations are 0.4 and 3.0 mM, respectively, which sugar is most likely to enter the cell through the transporter? Provide two reasons for your answer.
A student is working in a research lab studying the glucose transporter and evolution of this...
A student is working in a research lab studying the glucose transporter and evolution of this trans-membrane protein. There is genetic evidence that this transporter may be present in ancient bacteria but so far no functional data. The student designs an experiment where the cells are grown in a monolayer on a semi-permeable membrane on O-rings then placed in a chamber where 13C glucose flux (rate of transport/unit area) is monitored. Experiment is setup to monitor flux of glucose into...
In some cells glucose can be taken up by two different transport systems: facilitated diffusion and...
In some cells glucose can be taken up by two different transport systems: facilitated diffusion and glucose/proton symporter. a) Why is glucose not taken up by passive diffusion but by means of permeases? Describe the composition and structure of the permeases. b) Distinguish between facilitated diffusion and carbohydrate/proton symporter. The energy used to promote the active transport is the sum of the concentration-dependent energy (R∙T∙lnK) and the electrical work (z∙F∙ΔV). This process is usually linked directly or indirectly to ATP...
In some cells glucose can be taken up by two different transport systems: facilitated diffusion and...
In some cells glucose can be taken up by two different transport systems: facilitated diffusion and glucose/proton symporter. a) Why is glucose not taken up by passive diffusion but by means of permeases? Describe the composition and structure of the permeases. b) Distinguish between facilitated diffusion and carbohydrate/proton symporter. The energy used to promote the active transport is the sum of the concentration-dependent energy (R∙T∙lnK) and the electrical work (z∙F∙ΔV). This process is usually linked directly or indirectly to ATP...
The Na –glucose symport system of intestinal epithelial cells couples the \"downhill\" transport of two Na...
The Na –glucose symport system of intestinal epithelial cells couples the \"downhill\" transport of two Na ions into the cell to the \"uphill\" transport of glucose, pumping glucose into the cell against its concentration gradient. If the Na concentration outside the cell ([Na ]out) is 159 mM and that inside the cell ([Na ]in) is 23.0 mM, and the cell potential is -49.0 mV (inside negative), calculate the maximum ratio of [glucose]in to [glucose]out that could theoretically be produced if...
Choose either the sodium-potassium transport mechanism or the sodium-glucose transport mechanism. The file can be either...
Choose either the sodium-potassium transport mechanism or the sodium-glucose transport mechanism. The file can be either a diagram you create yourself or an essay format answer to the question. Depict or describe the process and mechanism of the transport you choose. Make sure to indicate the overall outcome, where the energy comes from, and how the membrane protein(s) facilitate the transport process. If you choose a diagram, make sure to clearly indicate the inside vs. the outside of the cell.
Na+ gradient across the cell membrane drives the transport of most nutrients, including glucose and amino...
Na+ gradient across the cell membrane drives the transport of most nutrients, including glucose and amino acids, into animal cells. Describe how Na+ supports this process. What type of transport is this? Also, explain how Na+ gradient across the membrane is maintained.
1.If glucose is ALWAYS present at higher concentrations outside the cell than inside the cell, explain...
1.If glucose is ALWAYS present at higher concentrations outside the cell than inside the cell, explain why it needs its own transporter protein to get into
14) Consider the oxidation of glucose to carbon dioxide and water and the production of ATP...
14) Consider the oxidation of glucose to carbon dioxide and water and the production of ATP a. How many electrons pass through the mitochondrial electron transport chain per glucose molecule oxidized? b. How many protons are pumped in the process? Remember that not all electrons go through NADH. c. How much energy would be stored per mole of glucose by the resulting membrane potential at 37C (assume that the pH is 0.5 units lower on the outside than on the...
#1. Stage 3 to 4 cancer cells are vicious in that they use up most glucose...
#1. Stage 3 to 4 cancer cells are vicious in that they use up most glucose in the body leaving normal cells to starve and die. Why is that so? A) Cancer cells are more efficient in converting glucose to ATP whereas normal cells are inefficient at this task leaving them disadvantaged B) Normal cells don’t like to make ATP from glucose whereas cancer cells do C) Advanced cancer cells are highly metabolic and use up excess glucose in glycolytic...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT