Question

A home kit to test for BRCA1 and 2 other genetic markers tests for 3 markers...

A home kit to test for BRCA1 and 2 other genetic markers tests for 3 markers out of possibly 1000 markers. What are your thoughts? Consider sensitivity and specificity of such a test.

Homework Answers

Answer #1

BRCA 1 and 2 are genes that are susceptible for breast cancer. Any mutations in these genes can lead to breast cancer or can increase the risk of breast cancer. As the number of people affecting breast cancer is escalating day by day, a home kit to test BRCA 1 and 2 genes gains very much significance. Genetic markers are also used to find the type of breast cancers. An early diagnosis or prediction of breast cancer is possible with help of this home kit test and genetic markers.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
A young woman in a suspected breast cancer family takes the BRCA1 and BRCA2 genetic tests....
A young woman in a suspected breast cancer family takes the BRCA1 and BRCA2 genetic tests. As a genetics counselor, you are asked to meet with her. She wants to meet with you to see if you can give her more information as to what are the different cancer types she is at higher risk for if in fact she test positive for a BRCA-1 or BRCA-2 mutation. A week later she receives her results and they are negative (she...
3. A diagnostic test has 95% sensitivity (the probability a person with the condition tests positive...
3. A diagnostic test has 95% sensitivity (the probability a person with the condition tests positive = 0.95) and 95% specificity (the probability a person without the condition tests negative = 0.95). In a population of people given the test, 1% of the people have the condition (probability a person has the condition = 0.01). (a) What proportion of the people will test positive? (b) Given a person has tested positive, what is the probability he/she has the condition?
We have an illness, where 2% of the polulation is infected, and we have a test...
We have an illness, where 2% of the polulation is infected, and we have a test with sensitivity 94% and specificity 98%. A="infected" and B="tests positive" The question: What is the probability that a test-subject tests positive, even when not infected? And how high does the specificity need to be such that the probability is below 10%
There are divisibility tests by 3, 9, and 11 as well as Divisibility tests for 2,...
There are divisibility tests by 3, 9, and 11 as well as Divisibility tests for 2, 4, and 8 (and other powers of 2) which are relatively easy, and divisibility by 5 is even easier. Explore: What else is out there? Why do we not need a separate divisibility test for 6 or 22 or 36? Is there a divisibility-by-7 test analogous to the ones for 9 and 11?
We have an illness, where 2% of the polulation is infected, and we have a test...
We have an illness, where 2% of the polulation is infected, and we have a test with sensitivity 94% and specificity 98%. A="infected" and B="tests positive" Question: 20 people gets tested, and all tests negative. What is the probability that atleast one of these 20 really are infected?
The RDT SARS-COV-2 test has 93.8 sensitivity (the probability of a true positive result) and 95.6%...
The RDT SARS-COV-2 test has 93.8 sensitivity (the probability of a true positive result) and 95.6% specificity (the probability of a true negative result) . Suppose that 10% of population is infected with SARS-COV-2. If a randomly selected individual tests positive, what is the probability he or she is infected?
The prevalence of a disease D among the population is 3%. There is a diagnostic test...
The prevalence of a disease D among the population is 3%. There is a diagnostic test for disease D. The sensitivity of this test is 99%, this means that the test is positive given that the person has the disease. The specificity of this test is 98%, this means that the test is negative given that the person does not have the disease. a) Given that a person tests positive, what is the probability that the person does not have...
Excerpt: “Blood tests [for herpes] can be highly unreliable. The kind of test used to diagnose...
Excerpt: “Blood tests [for herpes] can be highly unreliable. The kind of test used to diagnose Lauren, an IgM test, has long been rejected by the Centers for Disease Control and Prevention but is still used by some clinicians. Meanwhile, the CDC and the US Preventive Services Task Force concur that the most widely available herpes test, called HerpeSelect, should not be used to screen asymptomatic people because of its high risk of false positives: Up to 1 in 2...
You will be assessing the appropriateness of a new screening test for Disease X. Assume a...
You will be assessing the appropriateness of a new screening test for Disease X. Assume a population of 1000 people of whom 100 have Disease X and 900 do not have Disease X to answer questions a through i using the following 2x2 table: Disease No Disease Positive screen 80 100 Negative screen 20 800 1.      Calculate the sensitivity. 2.      Interpret your sensitivity calculation and the implications for potential use of this screening test. 3.       Calculate the specificity. 4.      Interpret your specificity calculation and...
The Food and Drug Administration does not regulate these tests, but White House coronavirus task force...
The Food and Drug Administration does not regulate these tests, but White House coronavirus task force coordinator Dr. Deborah Birx has said that she expects manufacturers to achieve a standard of 90% specificity (and 90% sensitivity, another measure of test performance that's less important in this context). Here's what would happen if you used a test with 90% specificity in a population in which only 1% of the people have coronavirus. Nobody knows for sure, but that could be the...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT