Question

A 60-year-old patient who is administered digoxin has developed severe digitalis toxicity. What is the usual...

A 60-year-old patient who is administered digoxin has developed severe digitalis toxicity.

  1. What is the usual treatment for this condition?

  2. What new drugs are being used to treat heart failure that reduce hospitalizations associated with chronic heart failure?

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Answer #1

1) The primary treatment of digoxin toxicity is digoxin immune fab, which is an antibody made up of anti-digoxinimmunoglobulin fragments. This antidote has been shown to be highly effective in treating life-threatening signs of digoxin toxicity such as hyperkalemia, hemodynamic instability, and arrhythmias.

2) The I(f) "funny current" inhibitor, ivabradine (Corlanor) received FDA approval in 2015 to reduce the risk ofhospitalization for worsening heart failure in patients with stable, symptomatic chronic heart failure with an LVEF of 35% or lower, who are in sinus rhythm with a resting heart rate of 70 bpm or higher

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