Question

People have often wondered: are there OTC insulins? If so, how many are there?

find one (1) OTC insulin. Give the brand and generic name (if available), how the drug is supplied and given (dosage form, strength, frequency, and ROA), how the drug works (MOA).

Answer 1

There are three otc insulin's -

names are a) regular acting (short acting )

b) NPH ( intermediate acting )

c ) a premixed combination of NPH and regular called 70-30

Under the brand name of (Relion)

Supplied as 100units /ml (3ml vial)

100units/ml (10ml vial )

Given as dosage , form strength , frequency and ROA

1) subcutaneous injection-

0.2-0.4 units /kg/day SC divided 8hr or more frequently.
maintaenance - 0.5 -1 unit /kg / day SC 8hrly

as 2) insulin pumps

3) iv infusion - dose needs to individualised .
Mode of action - by stimulating peripheral glucose uptake primarily by skeletal muscle cells and fat , and by inhibiting glucose production and release by the liver . It inhibits lipolysis , proteolysis and gluconeogenesis .