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What happens to the reading frame of a gene if a nucleotide is deleted? Select the...

What happens to the reading frame of a gene if a nucleotide is deleted? Select the single best answer. (A and E I know are incorrect)

A. the reading frame is shifted by one codon

B. the reading frame is shifted by three codons

C. the reading frame is shifted by one nucleotide

D. the reading frame is not changed

E. The reading frame is shifted by three nucleotides

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Answer #1

When a nucleotide is wrongly inserted or deleted, from a codon there could be many changes that takes place.Because 3 nucleotides together considered as 1 codon.If one nucleotide is removed, the the other two codon bases gets affected.This insertion and deletion of nucleotides are called frame shift mutations.

So the reading frame is shifted by 1 codons.Option C is correct.

Rationale : Eg: 3 Nucleotides = 1 codon

So if 1 nucleotide is deleted automatically it is shifted by one nucleotide making different sets.

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