amikacin
generic name: aminoglycoside antibiotic
brand name: arikayce, amikin, amiglyde-v
type of drug: aminoglycoside
pregnancy category: d
therapeutic action: it inhibits bacterial growth by binding to ribosomal subunits and interfers with binding of mrna and trna acceptor sites.
indications: infections with pseudomonas, e.coli, klebsiella, serratia, proteus.
contraindications: hypersensitivity
dose:
neonates less than 7 days -15-18mg/kg through iv / im
neonates more than 7 days - 18mg/kg through iv/ im
adverse effects:nephrotoxicity, neural damage, ototoxicity, autonomic disturbances, leukopenia
interactions: cisplatin, vancomycin, neostigmine, cephalosporin, amphotericin
nursing considerations:
perform blood tests
monitor peak levels
check for adverse effects
advice patient to take more fluids to avoid renal damage
patient education:
drink plenty of fluids while taking amikacin
do not mix amikacin with other medicines
do blood test and urine tests to find if in case of any toxicity
store medicine at room temperature
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