Question

1- What is the major ADR associated with 17 alpha alkylated testosterone agents?

2- FSH/ LH analogs should be given for a longer amount of timein order to produce enough viable sperm for IVF. (True or False)

3- Avoid contact with androgens if pregnant (true/ false)

4- The 5 alpha reductase inhibitors (finasteride/ Dutasteride) decrease DHT levels in about ---- hours after the first dose.

5- How long does it take to see adequate sperm number for traditional contraception?

Answer 1

1. Hepatotoxicity is the major ADR associated with Oxymetholone.

2. Yes, FSH/ LH analogues should be given for a longer amount of time in order to produce enough viable sperm for IVF. Because FSH/LH is effective in stimulating spermatogenesis.

3. The statement is false because androgens are the one which helps the pregnancy and the process of parturition.

4. The 5 alpha-reductase inhibitors (finasteride/ Dutasteride) decrease DHT levels in about 5-6 hours after the first dose. Because finasteride has a halflife of 5-6 hours.

5. It takes 3-6 days to see adequate sperm count for traditional contraception.