Question

differences in 4 main actions a drug has after binding to a receptor

Answer 1

There are 4 main types of actions of drug are seen after binding with the receptors. They are -

i. Stimulation

ii. Depression

iii. Replacement

iv. Cytotoxic effect.

The drugs that are bindas with various receptors of our body shows their action by some steps. The receptor may present in cell surface, cytoplasm or in nucleus. The drug in the circulation binds with the receptors of the cells. They form a drug-receptor complex. Then the response of the drug is shown.

The actions are different from each other. They are described below =

I. Stimulation = In this case the drugs increase the way the nerve cells normally send, receive or process the information. Example - the drug adrenaline stimulates the heart resulting in increased in heart rate and force of construction.

ii. Depression = this types of drugs shows their action by inhibiting some specific organs or organ system.

Example barbiturates, alcohol, general anaesthetics are depress the action of central nervous system.

iii. Replacement = these types of drugs acts by replacing some deficit endogenous substance.

Example in case of Insulin hormone deficiency the synthetic hormones is replaced by subcutaneous insulin injection.

iv. Cytotoxic action = these types of drugs perform their actions by killing the microorganisms or cancer cells.

Example - antibiotics likes as Azithromycin, Amoxicillin etc and anticancer drugs likes as Cisplatin, Carboplatin, cyclophosphamide etc.