Question

The following question pertains to biochemistry

A)Which of the following best describes the role of the zinc metal ion in carbonic anhydrase?

1. It dramatically shifts the reaction equilibrium toward the formation of carbonic acid.

2.It helps make water a better nucleophile

3.It increase the pka of water

4.It helps to coordinate atp which ultimately provides energy for the difficult reaction

5.It is purely structural and plays no direct role in catalysis

B)Which of the following statements is correct?

1.enzyme that catalyzes the addition of water to a double bond (to form an alcohol) is like an oxidoreductase

2.The eyring equation relates the equilibrium constant K with the Gibbs free energy of activation

3. Enzymes are generally equally active on D and L isomers of a given substrate

4. Substrate binding may induce a conformational change in an enzyme

5. More than one of these is correct. (indicate which ones are correct)

Please explain your asnwer choices for each

Answer 1

A) the following statement best describes the role of the zinc metal ion in carbonic anhydrase,

2.It helps make water a better nucleophile

It helps release more H+ in medium.

B) the following statements is correct,

2.The eyring equation relates the equilibrium constant K with the Gibbs free energy of activation

The erying eqaytion related equilibrium constant with free energy as an exponential term.

4. Substrate binding may induce a conformational change in an enzyme

Enzymes undergo conformational changes during the reaction when it binds to an substrate. This can assist or may reduce rate of reaction depending on several other factors.

5. More than one of these is correct. (indicate which ones are correct)