Question

one over the counter product lists the active ingredient as "diphenhydramine HCL". Wrote the acid base...

one over the counter product lists the active ingredient as "diphenhydramine HCL". Wrote the acid base reaction to illustrate how this compound is produced. when this product is dissolved in water would you expect it to be acidic, basic, or neutral? Explain?

Homework Answers

Answer #1

The acid-base reaction leading to the formation of diphenhydramine HCl is shown in the figure above. Diphenhydramine is a base due to the presence of –NR2 group while HCl is a strong acid. There is simply a protonation involving the non-bonding electron pair over the amine nitrogen.

When diphenhydramine HCl is dissolved in water, the solution is expected to be neutral to weakly acidic. This is due to the fact that diphenhydramine is a weak base while hydronium ion (H3O+) is a strong acid.

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